US 6,982,088 B2
Vaccine composition and stabilization method using high molecular weight PVP
Alain Françon, Bessenay (France); and Catherine Noël, Ecully (France)
Assigned to Aventis Pasteur, S.A., Lyon Cedex (France)
Appl. No. 10/381,948
PCT Filed Oct. 08, 2001, PCT No. PCT/FR01/03097
§ 371(c)(1), (2), (4) Date Mar. 31, 2003,
PCT Pub. No. WO02/28362, PCT Pub. Date Apr. 11, 2002.
Claims priority of application No. 00/12805 (FR), filed on Oct. 06, 2000.
Prior Publication US 2003/0190331 A1, Oct. 09, 2003
Int. Cl. A61K 39/12 (2006.01)
U.S. Cl. 424—204.1 16 Claims
 
1. A method for stabilizing over time a vaccine composition in the liquid state, the method comprising combining the vaccine composition with high-molecular-weight polyvinylpyrrolidone having a molecular weight greater than or equal to 100,000.