US 6,982,354 B2
Preparation of ketone containing cyclic compounds
Jegadeesh Thampi, Karnataka (India); Umesh Krishna Hasyagar, Karnataka (India); Anju S. Shukla, Maharashtra (India); and Pramod Kumbhar, Karnataka (India)
Assigned to General Electric Company, Schenectady, N.Y. (US)
Filed on Feb. 02, 2004, as Appl. No. 10/770,001.
Prior Publication US 2005/0171386 A1, Aug. 04, 2005
Int. Cl. C07C 45/38 (2006.01)
U.S. Cl. 568—361 25 Claims
 
1. A method of preparing a polycyclic compound containing a ketone functionality comprising:
reacting a mixture comprising a catalyst, a reactant compound and an amount of water greater than or equal to 3 weight percent based on the weight of the reactant compound; wherein said catalyst comprises nickel and base and said reactant compound comprises at least two fused rings, A and B wherein ring A is a saturated ring or ring system having 5 to 7 cyclic carbons and substituted with a hydroxyl functionality and ring B is a non-aromatic unsaturated ring having 5 to 6 cyclic carbons; and
converting the hydroxyl functionality of ring A to a ketone functionality and the non-aromatic unsaturated ring B to a saturated ring.