US 6,982,281 B1
Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
Feng-Jing Chen, Salt Lake City, Utah (US); and Mahesh V. Patel, Salt Lake City, Utah (US)
Assigned to Lipocine Inc, Salt Lake City, Utah (US)
Filed on Nov. 17, 2000, as Appl. No. 9/716,029.
Int. Cl. A61K 31/355 (2006.01); A61K 31/35 (2006.01); A61K 31/235 (2006.01); A61K 9/48 (2006.01); A61K 9/66 (2006.01)
U.S. Cl. 514—458 33 Claims
 
1. A pharmaceutical composition for oral administration of fenofibrate, comprising:
a) a therapeutically effective amount of fenofibrate; and
b) an effective solubilizing amount of a solubilizer selected from the group consisting of: a trialkyl citrate; a lactone; a combination of a trialkyl citrate and a lactone; a combination of a vitamin E substance and at least one of a trialkyl citrate and a lactone, and a combination of a nitrogen-containing solvent and at least one of a trialkyl citrate and a lactone.