US 6,982,281 B1 | ||
Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs | ||
Feng-Jing Chen, Salt Lake City, Utah (US); and Mahesh V. Patel, Salt Lake City, Utah (US) | ||
Assigned to Lipocine Inc, Salt Lake City, Utah (US) | ||
Filed on Nov. 17, 2000, as Appl. No. 9/716,029. | ||
Int. Cl. A61K 31/355 (2006.01); A61K 31/35 (2006.01); A61K 31/235 (2006.01); A61K 9/48 (2006.01); A61K 9/66 (2006.01) |
U.S. Cl. 514—458 | 33 Claims |
1. A pharmaceutical composition for oral administration of fenofibrate, comprising:
a) a therapeutically effective amount of fenofibrate; and
b) an effective solubilizing amount of a solubilizer selected from the group consisting of: a trialkyl citrate; a lactone;
a combination of a trialkyl citrate and a lactone; a combination of a vitamin E substance and at least one of a trialkyl citrate
and a lactone, and a combination of a nitrogen-containing solvent and at least one of a trialkyl citrate and a lactone.
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