US 6,982,282 B2
Emulsion vehicle for poorly soluble drugs
Karel J. Lambert, Seattle, Wash. (US); Panayiotis P. Constantinides, Gurnee, Ill. (US); and Steven C. Quay, Edmonds, Wash. (US)
Assigned to Sonus Pharmaceuticals, Inc., Bothell, Wash. (US)
Filed on May 17, 2002, as Appl. No. 10/151,079.
Application 10/151079 is a continuation of application No. 09/003173, filed on Jan. 05, 1998, granted, now 6,458,373.
Claims priority of provisional application 60/034188, filed on Jan. 07, 1997.
Claims priority of provisional application 60/048840, filed on Jun. 06, 1997.
Prior Publication US 2003/0104015 A1, Jun. 05, 2003
Int. Cl. A61K 31/337 (2006.01); A61P 35/00 (2006.01)
U.S. Cl. 514—511 23 Claims
 
1. A method of administering a chemotherapeutic agent to a subject suffering from cancer, comprising:
providing a pharmaceutical composition comprising a chemotherapeutic agent, wherein the chemotherapeutic agent is at least one of a taxoid, a taxane, or a taxine; α-tocopherol; a tocopherol polyethylene glycol succinate; and an aqueous phase; wherein the composition is an emulsion or a microemulsion having an oil phase and a water phase, and wherein all of the chemotherapeutic agent is in the oil phase; and
administering the pharmaceutical composition in a therapeutically effective amount to a subject suffering from cancer.