US 7,321,070 B2
Synthesis of isotopically labeled R- or S-[13C, 2H] glycerols
Rodolfo A. Martinez, Santa Fe, N. Mex. (US); Clifford J. Unkefer, Los Alamos, N. Mex. (US); and Marc A. Alvarez, Santa Fe, N. Mex. (US)
Assigned to Los Alamos National Security, LLC, Los Alamos, N. Mex. (US)
Filed on Jul. 30, 2003, as Appl. No. 10/629,982.
Prior Publication US 2005/0027146 A1, Feb. 03, 2005
Int. Cl. C07C 31/22 (2006.01)
U.S. Cl. 568—852  [568/853; 568/868; 568/869] 15 Claims
 
1. An asymmetric chiral labeled glycerol selected from the group consisting of (2S) [2-13C]glycerol and (2R) [2-13C]glycerol and from one to four deuterium atoms bonded directly to a carbon atom with the proviso that where there is only one deuterium atom, it is bonded to a terminal carbon atom.