US 6,093,302 C1 (6104th) | ||
ELECTROCHEMICAL SOLID PHASE SYNTHESIS | ||
Donald D. Montgomery, Millbrae, Calif., assignor to Nanogen, Inc., San Diego, Calif. | ||
Reexamination Request No. 90/008,259, Oct. 4, 2006. | ||
Reexamination Certificate for Patent 6,093,302, issued Jul. 25, 2000, Appl. No. 3,075, Jan. 5, 1998. | ||
Int. Cl. B01J 19/00; |
U.S. Cl. 205—122 |
AS A RESULT OF REEXAMINATION, IT HAS BEEN DETERMINED THAT: |
The patentability of claims 1-14 and 45-48 is confirmed. |
Claims 15, 16, 40 and 41 are determined to be patentable as amended. |
Claims 17-39 and 42-44, dependent on an amended claim, are determined to be patentable. |
1. A method for electrochemical placement of a material at a specific location on a substrate, which comprises the steps of: providing a substrate having at its surface at least one electrode that is proximate to at least one molecule bearing at least one protected chemical functional group,
placing a buffering or scavenging solution in contact with the electrode at the surface of the substrate to prevent the electrochemically generated reagents from leaving the locality of the electrode,
applying a potential to the electrode sufficient to generate electrochemical reagents capable of deprotecting at least one of the protected chemical functional groups, and
bonding the deprotected chemical functional group with a monomer of a pre-formed molecule.
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