US 7,320,777 B2
PCR sample handling device
Gary L. Bordenkircher, Livermore, Calif. (US); Gary Lim, San Francisco, Calif. (US); and Jacob Koppel Freudenthal, Alameda, Calif. (US)
Assigned to Applera Corporation, Foster City, Calif. (US)
Filed on Nov. 22, 2002, as Appl. No. 10/301,870.
Application 10/301870 is a continuation of application No. 09/897500, filed on Jul. 03, 2001, granted, now 6,514,750.
Prior Publication US 2003/0124714 A1, Jul. 03, 2003
This patent is subject to a terminal disclaimer.
Int. Cl. B01L 9/00 (2006.01); C12M 1/34 (2006.01)
U.S. Cl. 422—104  [435/287.2; 435/288.4; 435/809] 43 Claims
OG exemplary drawing
 
1. A device for handling at least one PCR substrate member in relation to a PCR instrument, the substrate member having an array of sample chambers closed by a translucent material on one side thereof, the device comprising:
a carrier having an apertured region with an array of holes substantially aligning with the array of sample chambers; and
a retention frame having an opening at least as large as the array of sample chambers and being fitted to the carrier to retain the substrate member in relation to the carrier,
wherein the carrier is constructed to contact the peripheral edge of the substrate member, and
wherein the substrate member comprises a microcard.