US 7,321,067 B2 | ||
Process for the preparation of 1,4-dialkyl-2,3-diol-1,4-butanedione | ||
Ferdinand Naef, Seewen (Switzerland); and René Decorzant, Onex (Switzerland) | ||
Assigned to Firmenich SA, Geneva (Switzerland) | ||
Filed on Mar. 28, 2007, as Appl. No. 11/692,839. | ||
Application 11/692839 is a continuation of application No. PCT/IB2005/053511, filed on Oct. 27, 2005. | ||
Claims priority of application No. PCT/IB2004/003631 (WO), filed on Nov. 02, 2004. | ||
Prior Publication US 2007/0167656 A1, Jul. 19, 2007 | ||
Int. Cl. C07C 45/72 (2006.01) |
U.S. Cl. 568—390 [568/392] | 7 Claims |
1. A process for the preparation of a compound of formula
![]() the process comprising performing an aldol condensation, in a water-containing reaction medium, between a glyoxal of formula
![]() and an α-hydroxy ketone of formula
![]() in the presence of catalyst of formula FeX3 or MX2, wherein M is Zn2+, Mg2+, Cu2+, Fe2+ or Ca2+ and X is a C1-C7 carboxylate, an halide or a acetylacetonate derivative of formula (R2COCHCOR2)−, with R2 representing a C1-C3 alkyl group or a phenyl group.
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