CPC C07K 16/2818 (2013.01) [A61K 9/0019 (2013.01); A61P 35/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/70 (2013.01); C07K 2317/75 (2013.01)] | 30 Claims |
1. An antibody or antigen-binding fragment thereof having binding specificity for programmed cell death receptor protein 1 (PD-1) comprising a light chain variable region and a heavy chain variable region, wherein the antibody or antigen-binding fragment comprises: CDR L1 comprising SEQ ID NO:114, CDR L2 comprising KVS, CDR L3 comprising SEQ ID NO:134, CDR H1 comprising SEQ ID NO:32, CDR H2 comprising SEQ ID NO:53, and CDR H3 comprising SEQ ID NO:74.
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