US 12,168,035 B2
C-terminal fragment of tetanus toxin (HC) for treatment of depression
Yousef Tizabi, Silver Spring, MD (US)
Assigned to Howard University, Washington, DC (US)
Filed by HOWARD UNIVERSITY, Washington, DC (US)
Filed on Apr. 26, 2022, as Appl. No. 17/729,502.
Application 17/729,502 is a division of application No. 16/878,809, filed on May 20, 2020, granted, now 11,338,016.
Prior Publication US 2022/0249602 A1, Aug. 11, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 38/16 (2006.01); A61K 9/00 (2006.01)
CPC A61K 38/164 (2013.01) [A61K 9/0019 (2013.01)] 4 Claims
 
1. A method for treating or mitigating depression in a patient having Parkinson's disease (PD), comprising administrating an effective amount of C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) to a subject in need thereof.