CPC G01N 33/6872 (2013.01) [C07K 16/22 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C12N 2510/02 (2013.01); G01N 2333/495 (2013.01)] | 5 Claims |
1. A polypeptide comprising a variant Fc region, wherein the variant Fc region comprises amino acid alterations in a parent Fc region at positions 234, 238, 264, 311, 330, and 343 according to EU numbering, wherein the parent Fc region comprises the amino acid sequence of any one of SEQ ID NO: 195-197, or 198, and wherein the variant Fc region comprises an amino acid sequence having at least 90% sequence identity to SEQ ID NO: 195-197, or 198, respectively.
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