CPC A61K 31/5575 (2013.01) [A61K 9/0048 (2013.01); A61K 9/06 (2013.01); A61K 9/08 (2013.01); A61K 31/18 (2013.01); A61K 31/216 (2013.01); A61K 31/565 (2013.01); A61K 31/57 (2013.01); A61K 47/02 (2013.01); A61K 47/34 (2013.01); A61K 47/38 (2013.01); A61P 27/02 (2018.01)] | 20 Claims |
1. A method of treating an ophthalmic condition or disease comprising administering an ophthalmic composition to a subject in need thereof, the ophthalmic composition comprising:
(i) about 0.015 wt % to about 1 wt % pilocarpine or a pharmaceutically acceptable salt of pilocarpine, and
ii deuterated water, wherein the ophthalmic composition comprises at least 95% deuterated water;
wherein the composition comprises a pD of about 4 to about 8; wherein the composition comprises at least about 80% pilocarpine based on initial concentration after at least about one week under storage conditions.
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