CPC A61F 9/0017 (2013.01) [A61N 1/0436 (2013.01); A61N 1/0448 (2013.01); A61N 1/325 (2013.01)] | 21 Claims |
1. A therapeutic agent delivery device comprising a polymeric substrate, wherein the polymeric substrate comprises:
a release region comprising:
one or more reservoirs configured to hold a therapeutic agent,
a mechanism configured to control a release of the therapeutic agent from the one or more reservoirs;
a delivery region in fluid communication with the release region configured to receive the therapeutic agent released from the one or more reservoirs, comprising a first ionophoresis electrode configured to transport the therapeutic agent released from the one or more reservoirs into a target tissue via electromigration, and
a receiving region comprising a second iontophoresis electrode configured to maintain electroneutrality within the target tissue,
wherein a circuit is formed between a current source, the first iontophoresis electrode, and the second ionophoresis electrode.
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