CPC A61K 39/125 (2013.01) [A61K 9/0019 (2013.01); A61P 31/12 (2018.01); C07K 14/005 (2013.01); A61K 2039/5258 (2013.01); A61K 2039/53 (2013.01); C12N 2770/16034 (2013.01)] | 28 Claims |
1. A pharmaceutical composition comprising at least one artificial RNA molecule and at least three different RNA coding regions encoding three different Norovirus VP1 polypeptides, said coding regions each encoding a different GII.4 VP1 polypeptide and having at least 90% identity to the polypeptide coding sequence of SEQ ID NOs: 39713-39721 or 39726-39738, wherein the at least one artificial RNA molecule comprises at least one heterologous 5′ and/or 3′ untranslated region (UTR).
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