US 12,168,671 B2
Phosphohistidine mimetics and antibodies to same
Tom W. Muir, Princeton, NJ (US); Rob C. Oslund, Princeton, NJ (US); and Jung-Min Kee, Ulsan (KR)
Assigned to THE TRUSTEES OF PRINCETON UNIVERSITY, Princeton, NJ (US)
Filed by The Trustees of Princeton University, Princeton, NJ (US)
Filed on Mar. 29, 2022, as Appl. No. 17/707,330.
Application 17/707,330 is a division of application No. 16/135,396, filed on Sep. 19, 2018, abandoned.
Application 16/135,396 is a division of application No. 15/026,670, granted, now 10,351,581, previously published as PCT/US2014/058758, filed on Oct. 2, 2014.
Claims priority of provisional application 61/885,657, filed on Oct. 2, 2013.
Prior Publication US 2022/0220134 A1, Jul. 14, 2022
Int. Cl. C07F 9/6503 (2006.01); C07K 16/44 (2006.01); G01N 33/53 (2006.01)
CPC C07F 9/65031 (2013.01) [C07K 16/44 (2013.01); G01N 33/5308 (2013.01); G01N 2800/26 (2013.01)] 1 Claim
 
1. A phosphonopyrazole of formula I:

OG Complex Work Unit Chemistry
wherein:
R is

OG Complex Work Unit Chemistry
R2, and R3, are each, independently, H or alkyl;
X is —CH2—CH2—;
Y is NHBoc, where Boc is tert-butoxycarbonyl protecting group.