CPC A61K 9/7084 (2013.01) [A61K 9/0014 (2013.01); A61K 9/7053 (2013.01); A61K 9/7061 (2013.01); A61K 9/7069 (2013.01); A61K 41/00 (2013.01); A61K 47/34 (2013.01); A61M 35/00 (2013.01); A61K 9/703 (2013.01)] | 11 Claims |
1. A method for treating Alzheimer's disease in a subject, comprising:
applying a transdermal patch to skin of the subject, wherein the transdermal patch is comprised of
a composite backing layer comprised of
(i) a first layer comprised of a polymer fabric or a polymer film comprised of one or more polymers selected from polyesters, and polyethylenes;
(ii) a second layer comprised of one or more adhesive polymers, the one or more adhesive polymers being acrylate copolymers; and
(iii) a third layer comprised of a polyethylene terephthalate/ethylene-vinyl acetate laminate;
wherein the first and second layers are in contact and the second and third layers are in contact, and
wherein the third layer comprises cuts formed at least partially through the third layer; and
an adhesive matrix drug layer laminated to the third layer, the adhesive matrix drug layer comprising donepezil.
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