US 12,169,427 B2
Methods and devices for manipulating temperature
Matthew J. Smith, Somerville, MA (US); Kristen Warren, Cambridge, MA (US); David Cohen-Tanugi, Somerville, MA (US); and Samuel Shames, Cambridge, MA (US)
Assigned to EMBR Labs IP LLC, Boston, MA (US)
Filed by EMBR Labs IP LLC, Boston, MA (US)
Filed on Jul. 28, 2023, as Appl. No. 18/361,385.
Application 18/361,385 is a continuation of application No. 17/109,749, filed on Dec. 2, 2020, granted, now 11,755,083.
Application 17/109,749 is a continuation of application No. 16/344,577, granted, now 11,256,309, previously published as PCT/US2017/060822, filed on Nov. 9, 2017.
Claims priority of provisional application 62/420,481, filed on Nov. 10, 2016.
Prior Publication US 2024/0053807 A1, Feb. 15, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. G05B 15/02 (2006.01); G06F 1/20 (2006.01); A61F 7/02 (2006.01)
CPC G06F 1/206 (2013.01) [G05B 15/02 (2013.01); A61F 7/02 (2013.01)] 30 Claims
OG exemplary drawing
 
1. A device for manipulating a temperature of a user's skin, the device comprising:
at least one thermoelectric element constructed and arranged to be disposed adjacent to a user's skin;
at least one sensor; and
at least one processor in electrical communication with the at least one thermoelectric element, the at least one processor configured to:
determine a sympathetic response associated with an autonomic nervous system of the user based on a signal received from the at least one sensor;
based at least in part on the determined sympathetic response, cause the at least one thermoelectric element to generate a thermal profile at a region of the at least one thermoelectric element adjacent to the user's skin to modify the sympathetic response of the autonomic nervous system of the user, wherein an applied temperature of the thermal profile is cyclically varied between a first temperature and a second temperature; and
modify the thermal profile in response to changes in the sympathetic response determined based on the signal received from the at least one sensor.