CPC C07K 16/4241 (2013.01) [C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01)] | 20 Claims |
1. An isolated antibody that specifically binds polymeric immunoglobulin A (pIgA), wherein the antibody comprises the following complementarity determining regions (CDRs):
(a) a CDR-H1 comprising the amino acid sequence of GFTFSNYG (SEQ ID NO: 1);
(b) a CDR-H2 comprising the amino acid sequence of INRGGDRI (SEQ ID NO: 2);
(c) a CDR-H3 comprising the amino acid sequence of RGLYYYGSDYYFDY (SEQ ID NO: 3);
(d) a CDR-L1 comprising the amino acid sequence of GNIHNY (SEQ ID NO: 4);
(e) a CDR-L2 comprising the amino acid sequence of NAK (SEQ ID NO: 5); and
(f) a CDR-L3 comprising the amino acid sequence of HHYYSTPYT (SEQ ID NO: 6).
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