CPC A61K 9/006 (2013.01) [A61K 9/0014 (2013.01); A61K 9/0043 (2013.01); A61K 9/08 (2013.01); A61K 9/107 (2013.01); A61K 9/7015 (2013.01); A61K 31/05 (2013.01); A61K 31/07 (2013.01); A61K 31/122 (2013.01); A61K 31/135 (2013.01); A61K 31/197 (2013.01); A61K 31/355 (2013.01); A61K 31/375 (2013.01); A61K 31/40 (2013.01); A61K 31/4045 (2013.01); A61K 31/4188 (2013.01); A61K 31/43 (2013.01); A61K 31/4415 (2013.01); A61K 31/505 (2013.01); A61K 31/51 (2013.01); A61K 31/525 (2013.01); A61K 31/565 (2013.01); A61K 31/568 (2013.01); A61K 31/57 (2013.01); A61K 31/573 (2013.01); A61K 31/592 (2013.01); A61K 31/593 (2013.01); A61K 31/675 (2013.01); A61K 31/714 (2013.01); A61K 33/00 (2013.01); A61K 33/06 (2013.01); A61K 33/26 (2013.01); A61K 33/30 (2013.01); A61K 33/32 (2013.01); A61K 33/34 (2013.01); A61K 33/42 (2013.01); A61K 36/185 (2013.01); A61K 38/05 (2013.01); A61K 38/28 (2013.01); A61K 47/10 (2013.01); A61K 47/12 (2013.01); A61K 47/14 (2013.01); A61K 47/44 (2013.01)] | 19 Claims |
1. A transmucosal and/or transdermal delivery system, comprising a micelle composition which comprises:
one or more surfactants, wherein the one or more surfactants consist of at least one non-ionic surfactant having a Hydrophile-Lipophile Balance (HLB) value of from about 12 to about 16;
at least one polyol;
at least one active agent;
at least one oil; and
water, at a ratio of said water to the at least one active agent, the at least one non-ionic surfactant and the at least one polyol that is from 4:1 to 1:1 by weight,
and wherein the micelle composition has: (i) a viscosity of from about 5 cP to about 35 cP when measured at 25° C. on a Brookfield viscometer with spindle #1 at 20 rpm; and (ii) an average particle size of from about 5 nm to about 200 nm.
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