CPC F16K 7/06 (2013.01) [B01D 61/12 (2013.01); B01D 61/22 (2013.01); F16K 7/07 (2013.01); G05D 16/2013 (2013.01); B01D 2311/04 (2013.01); B01D 2311/08 (2013.01); B01D 2311/14 (2013.01); B01D 2313/18 (2013.01)] | 9 Claims |
1. A crossflow filtration apparatus comprising a crossflow filter and a throttling assembly, the throttling assembly comprising:
a pump fluidically connected to a length of flexible tubing mounted in the pinch valve, the length of flexible tubing being coupled to the crossflow filter, the pinch valve comprising:
a valve body with a tubing holder,
a valve seat,
an actuator adapted to compress the flexible tubing in said tubing holder against said valve seat, and
a pneumatic or hydraulic actuator drive, and
a first pressure transducer adapted to measure a pressure in said length of tubing between said pump and said pinch valve, and
wherein the actuator is configured to move between a plurality of actuator positions at variable actuator velocities.
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