US 12,168,761 B2
Auxiliary manifold for a bioreactor
Kai Hoeffner, Medway, MA (US); Zheng Huang, Bolton, MA (US); Savitha Panikar, Lowell, MA (US); Orianna Elysse Kane, Boston, MA (US); Zachary Allen Corriveau, Worcester, MA (US); and William Fabrizio, Enfield, CT (US)
Assigned to Ark Biotech Inc., Westwood, MA (US)
Filed by Ark Biotech Inc., Westwood, MA (US)
Filed on Apr. 28, 2023, as Appl. No. 18/140,827.
Claims priority of provisional application 63/345,270, filed on May 24, 2022.
Prior Publication US 2023/0383227 A1, Nov. 30, 2023
Int. Cl. C12M 1/00 (2006.01); C12M 1/36 (2006.01)
CPC C12M 23/40 (2013.01) [C12M 23/34 (2013.01); C12M 29/04 (2013.01); C12M 41/48 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A manifold, comprising:
a controller;
a tube;
a sample chamber to temporarily store a sample of bulk material stored in a cell culture vessel growing cell culture;
a first valve positioned in between a sterile filter and an exhaust, wherein the sterile filter is positioned in between the sample chamber and the first valve;
a second valve positioned in between the sterile filter and a gas inlet, wherein the sterile filter is located in between the sample chamber and the second valve; and
at least a first probe included in the sample chamber, wherein the at least the first probe, the first valve, and the second valve are coupled to the controller,
wherein the at least the first probe is configured to measure a corresponding value associated with the sample of the bulk material provided from the cell culture vessel to the sample chamber via the tube, wherein the manifold is attached to a port associated with the cell culture vessel via the tube.