US 12,167,932 B2
Categorization of ultrasound waveforms through morphological variables
Samuel G. Thorpe, Los Angeles, CA (US); Corey M. Thibeault, Los Angeles, CA (US); Nicolas Canac, Los Angeles, CA (US); and Kian Jalaleddini, Los Angeles, CA (US)
Assigned to Neurasignal, Inc., Los Angeles, CA (US)
Filed by Neurasignal, Inc., Los Angeles, CA (US)
Filed on Jan. 31, 2023, as Appl. No. 18/104,188.
Application 18/104,188 is a continuation of application No. 16/792,169, filed on Feb. 14, 2020, granted, now 11,596,380.
Claims priority of provisional application 62/806,229, filed on Feb. 15, 2019.
Prior Publication US 2023/0363734 A1, Nov. 16, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 8/08 (2006.01); A61B 8/06 (2006.01)
CPC A61B 8/0808 (2013.01) [A61B 8/06 (2013.01); A61B 8/488 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A method of processing an ultrasound signal, the method comprising:
processing the ultrasound signal into a waveform, the ultrasound signal corresponding to blood flow within a blood vessel of a subject;
identifying three morphological variables of the waveform processed from the ultrasound signal, wherein the three morphological variables comprise:
a first variable comprising an absolute peak onset of the waveform;
a second variable comprising a length of a canopy of the waveform; and
a third variable comprising a number of auxiliary peaks of the waveform and/or prominence of the auxiliary peaks of the waveform;
mapping the three morphological variables to a point within a three-dimensional space;
determining, based on the point in the three-dimensional space, a probability that the morphological variables of the waveform corresponds to a category associated with a blood vessel condition;
determining that the waveform is indicative of belonging to the category; and
displaying the probability that the waveform belongs to the category.