US 12,168,806 B2
Full-automatic detection apparatus and system for important zoonotic pathogen, and control method for full-automatic detection apparatus for important zoonotic pathogen
Jiabo Ding, Beijing (CN); Xiaowen Yang, Beijing (CN); Hui Jiang, Beijing (CN); Lin Liang, Beijing (CN); Ting Xin, Beijing (CN); Guangzhi Zhang, Beijing (CN); Xuezheng Fan, Beijing (CN); and Qingchun Shen, Beijing (CN)
Assigned to Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing (CN)
Filed by Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing (CN)
Filed on Aug. 28, 2023, as Appl. No. 18/456,540.
Claims priority of application No. 202211049188.X (CN), filed on Aug. 30, 2022.
Prior Publication US 2024/0068056 A1, Feb. 29, 2024
Int. Cl. C12Q 1/70 (2006.01); C12Q 1/689 (2018.01); G01N 1/22 (2006.01); G01N 33/00 (2006.01); C12Q 1/6851 (2018.01)
CPC C12Q 1/701 (2013.01) [C12Q 1/689 (2013.01); G01N 1/2205 (2013.01); G01N 33/0011 (2013.01); G01N 33/0073 (2013.01); C12Q 1/6851 (2013.01)] 3 Claims
OG exemplary drawing
 
1. A fully automatic detection apparatus for zoonotic pathogen detection, the apparatus comprising:
a base capable of moving and comprising a tire;
an air collection device, arranged on the base and configured to collect a to-be-detected sample in air during movement of the base, wherein the air collection device comprises multiple filter membranes, filter holes of each of the multiple filter membranes have different sizes and each of the multiple filter membranes is configured to filter one selected from the group consisting of bacteria, molds, fungi, viruses and spores of the to-be-detected sample in the air;
a nucleic acid detection and analysis device, arranged on the base and connected to the air collection device through a draft tube; wherein the nucleic acid detection and analysis device is configured to receive the to-be-detected sample from the air collection device through the draft tube and detect the to-be-detected sample to determine whether an infectious pathogen exists in the to-be-detected sample to obtain a detection result, wherein the nucleic acid detection and analysis device comprises multiple nucleic acid detection modules for determining whether the infectious pathogen exists in the to-be-detected sample;
a mobile device, arranged on the base and electrically connected to the base, wherein the mobile device comprises a navigation device, an obstacle detection device and a camera connected to the obstacle detection device, the navigation device is configured to receive, from a control device, a control instruction from a terminal and plan a target moving path and a target detection path of the base according to the control instruction, and the obstacle detection device is configured to, based on an image shot by the camera, detect an obstacle in the target moving path and control the base to avoid the obstacle, wherein the obstacle is an object that hinders the base from moving in target moving path; and
the control device, wherein the control device is configured for communication connection with the terminal and is electrically connected to the mobile device, the nucleic acid detection and analysis device and the air collection device; and the control device is configured to receive the control instruction from the terminal and further configured, according to the control instruction, to determine a target filter membrane for collecting the to-be-detected sample of the multiple filter membranes, a target nucleic acid detection module for detecting the to-be-detected sample of the nucleic acid detection modules and sampling time for sampling the to-be-detected sample, and the control device is configured to: transmit the control instruction to the mobile device to make the mobile device plan the target moving path and the target detection path of the base; and receive and transmit the detection result from the nucleic acid detection and analysis device to the terminal; wherein the target moving path is a path along which the base moves from a current position of the base to a target detection area, and the target detection path is a path along which the base moves in the target detection area; and the target detection path is a circular route or an S-shaped route;
wherein the control instruction comprises an infectious pathogen type, the target detection area and a detection period.