CPC A61K 31/19 (2013.01) [A61K 9/0053 (2013.01); A61K 9/009 (2013.01); A61K 9/0095 (2013.01)] | 26 Claims |
1. A method of decreasing excessive daytime sleepiness in a human subject in need thereof, the method comprising:
orally administering a pharmaceutical composition comprising first and second salts of gamma-hydroxybutyrate to said human subject, wherein
said first salt is selected from the group consisting of sodium oxybate, calcium oxybate, magnesium oxybate, and potassium oxybate,
said second salt differs from said first salt and is selected from the group consisting of sodium oxybate, calcium oxybate, magnesium oxybate, and potassium oxybate, and
wherein the orally administering occurs only once daily, and most adverse events (AEs) occur 1.5-2 hours after dosing.
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