CPC A61K 47/6879 (2017.08) [A61K 35/17 (2013.01); A61K 39/0011 (2013.01); A61K 39/395 (2013.01); A61K 48/00 (2013.01); C07K 14/7051 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/7151 (2013.01); C07K 16/2809 (2013.01); C07K 16/30 (2013.01); C07K 16/303 (2013.01); C07K 16/46 (2013.01); C07K 19/00 (2013.01); C12N 5/10 (2013.01); C12N 15/62 (2013.01); C12N 15/63 (2013.01); A61K 2039/5156 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01); G01N 33/57438 (2013.01)] | 26 Claims |
1. An antibody that specifically recognizes glypican-3, comprising within an antibody molecule:
a light chain variable region comprising VL CDR1 having the sequence of SEQ ID NO: 16, VL CDR2 having the sequence of SEQ ID NO: 18, and VL CDR3 having the sequence of SEQ ID NO: 20; and a heavy chain variable region comprising VH CDR1 having the sequence of SEQ ID NO: 10, VH CDR2 having the sequence of SEQ ID NO: 12, and VH CDR3 having the sequence of SEQ ID NO: 14.
|