CPC A61K 31/722 (2013.01) [A61K 31/136 (2013.01); A61K 31/137 (2013.01); A61K 31/4178 (2013.01); A61K 31/46 (2013.01); A61K 31/4745 (2013.01); A61K 31/522 (2013.01); A61K 31/573 (2013.01); A61K 31/58 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61P 31/14 (2018.01)] | 15 Claims |
1. A method of treating pathologies of the respiratory tract or hepatic pathologies, wherein said pathologies are characterized by inflammation and/or fibrosis, the method comprising the step of
administering to a subject in need thereof an effective amount of a functionalized chitosan, or a salt thereof, as anti-inflammatory and anti-fibrotic agent, said functionalized chitosan being a chitosan wherein at least 20% of D-glucosamine units have the formula (I):
![]() where R is a moiety of formula (1):
![]() wherein Z1 is —CH2— or —CO—,
Z2 is —OH, or —NHCOCH3,
Z3 is H, monosaccharide, disaccharide, or oligosaccharide,
or R is a moiety of formula (2):
![]() wherein Z4 is —CH—,
Z5 and Z6 are, independently of each other, H, monosaccharide, disaccharide, or oligosaccharide.
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