US 12,167,853 B2
Non-woven graft materials for nerve repair and regeneration
Matthew R. MacEwan, St. Louis, MO (US); Lily Jeng, St. Louis, MO (US); Abdolrasol Rahimi, St. Louis, MO (US); Manisha Jassal, West Warwick, RI (US); and Tamas Kovacs, St. Louis, MO (US)
Assigned to Acera Surgical, Inc., St. Louis, MO (US)
Filed by Acera Surgical, Inc., St. Louis, MO (US)
Filed on Sep. 6, 2022, as Appl. No. 17/903,918.
Claims priority of provisional application 63/241,366, filed on Sep. 7, 2021.
Prior Publication US 2023/0074964 A1, Mar. 9, 2023
Int. Cl. A61B 17/11 (2006.01); A61L 27/18 (2006.01); A61L 27/22 (2006.01); A61L 27/24 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/58 (2006.01)
CPC A61B 17/1128 (2013.01) [A61L 27/18 (2013.01); A61L 27/225 (2013.01); A61L 27/24 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61L 2300/412 (2013.01); A61L 2300/604 (2013.01); A61L 2430/32 (2013.01)] 54 Claims
OG exemplary drawing
 
1. A resorbable hybrid-scale fiber matrix for use in facilitating nerve repair and regeneration, the matrix comprising:
an inner fiber layer comprising uniaxially-aligned or longitudinally-aligned fibers; and
an outer fiber layer comprising randomly-aligned fibers,
wherein the hybrid-scale fibers comprise fibers having a range of fiber diameters between 10 nm-10,000 nm.