US 12,167,978 B2
Eye mounted device for therapeutic agent release
Christian Gutierrez, Pacifica, CA (US)
Assigned to Verily Life Sciences LLC, Dallas, TX (US)
Filed by Verily Life Sciences LLC, Dallas, TX (US)
Filed on Jul. 6, 2022, as Appl. No. 17/858,452.
Application 17/858,452 is a continuation of application No. 16/736,423, filed on Jan. 7, 2020, granted, now 11,399,976.
Claims priority of provisional application 62/790,313, filed on Jan. 9, 2019.
Prior Publication US 2022/0339029 A1, Oct. 27, 2022
Int. Cl. A61F 9/00 (2006.01); A61N 1/04 (2006.01); A61N 1/32 (2006.01)
CPC A61F 9/0017 (2013.01) [A61N 1/0436 (2013.01); A61N 1/0448 (2013.01); A61N 1/325 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A therapeutic agent delivery device comprising a polymeric substrate, wherein the polymeric substrate comprises:
a release region comprising:
one or more reservoirs configured to hold a therapeutic agent,
a mechanism configured to control a release of the therapeutic agent from the one or more reservoirs;
a delivery region in fluid communication with the release region configured to receive the therapeutic agent released from the one or more reservoirs, comprising a first ionophoresis electrode configured to transport the therapeutic agent released from the one or more reservoirs into a target tissue via electromigration, and
a receiving region comprising a second iontophoresis electrode configured to maintain electroneutrality within the target tissue,
wherein a circuit is formed between a current source, the first iontophoresis electrode, and the second ionophoresis electrode.