US 12,168,026 B2
Methods and compositions for wound healing
Nicholas L. Abbott, Madison, WI (US); and Jonathan F. McAnulty, Oregon, WI (US)
Filed by Nicholas L. Abbott, Madison, WI (US); and Jonathan F. McAnulty, Oregon, WI (US)
Filed on Oct. 3, 2023, as Appl. No. 18/376,044.
Application 18/376,044 is a continuation of application No. 17/268,622, granted, now 11,793,832, previously published as PCT/US2019/046831, filed on Aug. 16, 2019.
Claims priority of provisional application 62/718,988, filed on Aug. 16, 2018.
Prior Publication US 2024/0139237 A1, May 2, 2024
Int. Cl. A61K 33/38 (2006.01); A61K 9/70 (2006.01); A61K 31/167 (2006.01); A61K 31/381 (2006.01); A61K 31/445 (2006.01); A61K 33/24 (2019.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61L 15/28 (2006.01); A61L 15/44 (2006.01); A61P 17/02 (2006.01); A61P 31/02 (2006.01)
CPC A61K 33/38 (2013.01) [A61K 9/7092 (2013.01); A61K 31/167 (2013.01); A61K 31/381 (2013.01); A61K 31/445 (2013.01); A61K 33/24 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); A61L 15/28 (2013.01); A61L 15/44 (2013.01); A61P 17/02 (2018.01); A61P 31/02 (2018.01); A61L 2300/404 (2013.01); A61L 2300/61 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A method of treating a wound comprising applying a device to the surface of wound, the device comprising:
a first polymer layer comprising a first bioactive agent, wherein the first polymer layer is a nanoscale polymer multilayer comprising alternating layers of at least one positively charged polyelectrolyte and at least one negatively charged polyelectrolyte;
a second polymer layer comprising a second bioactive agent, wherein the second polymer layer is a water soluble microscale polymer layer; and
a third polymer layer positioned in between the first and second polymer layers so that the three polymer layers are stacked in a sandwich-type structure, wherein the third polymer layer is a water soluble microscale polymer layer formed from a different polymer than the second polymer layer.