US 12,167,961 B2
Methods and systems for aligning a commissure of a prosthetic heart valve with a commissure of a native valve
Michael R. Bialas, Lake Forest, CA (US)
Assigned to EDWARDS LIFESCIENCES CORPORATION, Irvine, CA (US)
Filed by EDWARDS LIFESCIENCES CORPORATION, Irvine, CA (US)
Filed on Feb. 24, 2023, as Appl. No. 18/113,833.
Application 18/113,833 is a continuation of application No. PCT/US2021/047056, filed on Aug. 23, 2021.
Claims priority of provisional application 63/138,890, filed on Jan. 19, 2021.
Claims priority of provisional application 63/069,567, filed on Aug. 24, 2020.
Prior Publication US 2023/0190456 A1, Jun. 22, 2023
Int. Cl. A61F 2/24 (2006.01); A61B 50/30 (2016.01); A61M 25/10 (2013.01); A61F 2/95 (2013.01); A61F 2/958 (2013.01)
CPC A61F 2/24 (2013.01) [A61B 50/30 (2016.02); A61F 2/2418 (2013.01); A61F 2/2436 (2013.01); A61M 25/10 (2013.01); A61F 2/2433 (2013.01); A61F 2/9517 (2020.05); A61F 2002/9583 (2013.01); A61F 2220/0025 (2013.01); A61F 2220/0075 (2013.01); A61F 2230/0002 (2013.01); A61F 2250/0098 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A method comprising:
advancing a distal end portion of a delivery apparatus toward a native valve of a heart, wherein a prosthetic heart valve is radially compressed around an inflatable balloon of the delivery apparatus, at a valve mounting portion of the delivery apparatus;
visualizing, under fluoroscopy and for a selected imaging view, a position of a radiopaque marker on the distal end portion of the delivery apparatus relative to a guidewire extending through a shaft of the delivery apparatus, wherein the marker is circumferentially offset from a selected commissure of the radially compressed prosthetic heart valve by a predetermined amount that is determined based on the selected imaging view, and wherein the marker is reflection asymmetric along an axis that is parallel to a central longitudinal axis of the delivery apparatus;
prior to crossing the native valve, rotating the shaft of the delivery apparatus, which rotates the prosthetic heart valve and the marker, until the marker is centered along the guidewire and is in a predetermined orientation in the selected imaging view; and
advancing the distal end portion of the delivery apparatus including the radially compressed prosthetic heart valve across and into the native valve and inflating the balloon to radially expand and implant the prosthetic heart valve in the native valve such that the selected commissure of the prosthetic heart valve is aligned with a target commissure of the native valve, wherein during the inflating, as the prosthetic heart valve radially expands, the prosthetic heart valve rotates.