US 12,168,033 B2
Synergistic composition for osteoarthritis
Ganga Raju Gokaraju, Vijayawada (IN); Rama Raju Gokaraju, Vijayawada (IN); Venkata Kanaka Ranga Raju Gokaraju, Vijayawada (IN); Trimurtulu Golakoti, Vijayawada (IN); and Kiran Bhupathiraju, Vijayawada (IN)
Assigned to LAILA NUTRACEUTICALS, Vijayawada (IN)
Filed by LAILA NUTRACEUTICALS, Vijayawada (IN)
Filed on Sep. 30, 2021, as Appl. No. 17/489,915.
Application 17/489,915 is a continuation of application No. 15/518,107, granted, now 11,147,850, previously published as PCT/IN2015/000382, filed on Oct. 9, 2015.
Claims priority of application No. 5106/CHE/2014 (IN), filed on Oct. 10, 2014.
Prior Publication US 2022/0096588 A1, Mar. 31, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 36/9066 (2006.01); A61K 9/00 (2006.01); A61K 31/353 (2006.01); A61K 31/715 (2006.01); A61K 36/48 (2006.01)
CPC A61K 36/9066 (2013.01) [A61K 9/0014 (2013.01); A61K 9/0053 (2013.01); A61K 31/353 (2013.01); A61K 31/715 (2013.01); A61K 36/48 (2013.01); A61K 2236/33 (2013.01)] 21 Claims
 
1. A method for treating at least one disease condition selected from the group consisting of inflammation, arthritis, joint pain, rheumatoid arthritis, osteoarthritis, chronic non-rheumatoid arthritis, and collagen degradation in a patient in need thereof, comprising administering to the patient an effective amount of a composition comprising:
a combination of therapeutically effective amounts of:
a) an alcohol or hydroalcohol extract of a Tamarindus indica seed, wherein the alcohol or hydroalcohol extract comprises proanthocyanidins; and
b) at least one of:
a water extract of the Tamarindus indica seed, the water extract comprising polysaccharides, wherein the alcohol or hydroalcohol extract of the Tamarindus indica seed and the water extract are used in a ratio ranging from 1:1 to 10:1; and
a Curcuma longa rhizome extract comprising curcuminoids, wherein the alcohol or hydroalcohol extract of the Tamarindus indica seed and the Curcuma longa rhizome extract are used in a ratio ranging from 1:4 to 4:1.