US 12,167,918 B2
Method and system for targeted and adaptive transcutaneous spinal cord stimulation
Yi-Kai Lo, Los Angeles, CA (US); Rachel Yung, Los Angeles, CA (US); Po-Min Wang, Los Angeles, CA (US); Alexander Barnes Baldwin, Los Angeles, CA (US); and Chia-Hung Ni, Los Angeles, CA (US)
Assigned to NICHE BIOMEDICAL, INC., Los Angeles, CA (US)
Appl. No. 17/762,800
Filed by NICHE BIOMEDICAL, INC., Los Angeles, CA (US)
PCT Filed Sep. 28, 2020, PCT No. PCT/US2020/052992
§ 371(c)(1), (2) Date Mar. 23, 2022,
PCT Pub. No. WO2021/062345, PCT Pub. Date Apr. 1, 2021.
Claims priority of provisional application 62/907,475, filed on Sep. 27, 2019.
Prior Publication US 2022/0386935 A1, Dec. 8, 2022
Int. Cl. A61B 5/389 (2021.01); A61B 5/00 (2006.01); A61B 5/01 (2006.01); A61B 5/021 (2006.01); A61B 5/024 (2006.01); A61B 5/11 (2006.01); A61B 5/145 (2006.01); A61N 1/04 (2006.01); A61N 1/36 (2006.01)
CPC A61B 5/389 (2021.01) [A61B 5/0075 (2013.01); A61B 5/1116 (2013.01); A61N 1/0456 (2013.01); A61N 1/36014 (2013.01); A61N 1/36031 (2017.08); A61B 5/01 (2013.01); A61B 5/021 (2013.01); A61B 5/024 (2013.01); A61B 5/14517 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A transcutaneous electrical stimulation system, comprising:
a plurality of electrodes configured to be in contact with a skin surface of a patient;
a flexible hub electrically connected to the electrodes and configured to be in contact with the patient;
a bend sensor disposed in the hub and configured to measure a curvature of the hub;
a signal processing device electrically coupled to the plurality of electrodes and the bend sensor, the signal processing device being configured to change stimulation settings of the plurality of electrodes based on the curvature of the hub, wherein a curvature signal from the hub is used to dynamically restrict stimulation intensity to sub-motor threshold levels; and
a multi-channel stimulator comprising at least one stimulation channel for each of the plurality of electrodes, the multi-channel stimulator being configured to receive the changed stimulation settings from the signal processing device and deliver electrical stimulation at each stimulation channel through its corresponding electrode.